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Men treated with cyclophosphamide may develop oligospermia or azoospermia associated with increased gonadotropin but normal testosterone secretionSexual potency and libido are unimpaired in these patientsBoys treated with cyclophosphamide during prepubescence develop secondary sexual characteristics normallybut may have oligospermia or azoospermia and increased gonadotropin secretionSome degree of testicular atrophy may occurCyclophosphamide-induced azoospermia is reversible in some patientsthough the reversibility may not occur for several years after cessation of therapyMen temporarily rendered sterile by cyclophosphamide have subsequently fathered normal children.


Cyclophosphamide is available in generic formand you need a prescription to obtain it.

Cytoxanalthough effective alone in susceptible malignanciesis more frequently used concurrently or sequentially with other antineoplastic drugsThe following malignancies are often susceptible to Cytoxan treatment:

The Cytoxan brand name has been discontinued in the U.SIf generic versions of this product have been approved by the FDAthere may be generic equivalents available.

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